Andrew N Lane Selected Research

Isotopes

11/2019	Inhibition of Anaplerotic Glutaminolysis Underlies Selenite Toxicity in Human Lung Cancer.
11/2019	NMR and MS-based Stable Isotope-Resolved Metabolomics and Applications in Cancer Metabolism.
1/2019	De novo synthesis of serine and glycine fuels purine nucleotide biosynthesis in human lung cancer tissues.
7/2018	Stable Isotope-Resolved Metabolomics Shows Metabolic Resistance to Anti-Cancer Selenite in 3D Spheroids versus 2D Cell Cultures.
1/2017	Exploring cancer metabolism using stable isotope-resolved metabolomics (SIRM).
1/2017	Probing the metabolic phenotype of breast cancer cells by multiple tracer stable isotope resolved metabolomics.
7/2016	Preclinical models for interrogating drug action in human cancers using Stable Isotope Resolved Metabolomics (SIRM).
7/2016	Distinctly perturbed metabolic networks underlie differential tumor tissue damages induced by immune modulator β-glucan in a two-case ex vivo non-small-cell lung cancer study.
1/2016	SDHB-Deficient Cancers: The Role of Mutations That Impair Iron Sulfur Cluster Delivery.
6/2012	Stable Isotope Resolved Metabolomics Analysis of Ribonucleotide and RNA Metabolism in Human Lung Cancer Cells.

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Andrew N Lane Research Topics

Disease

47	Neoplasms (Cancer) 01/2022 - 12/2004
13	Lung Neoplasms (Lung Cancer) 01/2021 - 01/2006
10	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2021 - 08/2009
5	Renal Cell Carcinoma (Grawitz Tumor) 01/2021 - 01/2013
5	Hypoxia (Hypoxemia) 01/2020 - 11/2007
5	Adenocarcinoma 11/2019 - 01/2008
4	Breast Neoplasms (Breast Cancer) 10/2018 - 01/2008
3	Leiomyomatosis 01/2021 - 01/2013
2	Inflammation (Inflammations) 01/2022 - 11/2015
2	Kidney Neoplasms (Kidney Cancer) 01/2021 - 01/2013
2	Carcinogenesis 01/2021 - 05/2014
2	Necrosis 11/2019 - 07/2016
2	Adenocarcinoma of Lung 01/2012 - 06/2011
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 04/2022
1	Disease Progression 01/2021
1	Neoplasm Metastasis (Metastasis) 01/2021
1	Hepatocellular Carcinoma (Hepatoma) 01/2020
1	Hypoglycemia (Reactive Hypoglycemia) 11/2019
1	Pancreatic Neoplasms (Pancreatic Cancer) 01/2019
1	Triple Negative Breast Neoplasms 10/2018
1	Iron Deficiencies 01/2018
1	Lymphatic Metastasis 11/2017
1	Colonic Neoplasms (Colon Cancer) 01/2017
1	Chronic Obstructive Pulmonary Disease (COPD) 07/2016

Drug/Important Bio-Agent (IBA)

16	IsotopesIBA 11/2019 - 02/2008
14	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 10/2009
9	EnzymesIBA 01/2021 - 06/2012
7	Pharmaceutical PreparationsIBA 01/2017 - 05/2014
6	Proteins (Proteins, Gene)FDA Link 04/2022 - 06/2009
6	Glutamine (L-Glutamine)FDA Link 01/2020 - 04/2011
6	Lactic Acid (Lactate)FDA LinkGeneric 01/2019 - 12/2007
5	Succinic Acid (Succinate)IBA 01/2022 - 06/2009
5	Adenosine Triphosphate (ATP)IBA 01/2020 - 01/2008
4	Fumarate Hydratase (Fumarase)IBA 01/2021 - 01/2013
4	Pyruvic Acid (Pyruvate)IBA 01/2020 - 03/2011
3	Transcription Factors (Transcription Factor)IBA 01/2022 - 06/2012
3	CarbonIBA 01/2022 - 01/2019
3	Succinate Dehydrogenase (Fumarate Reductase)IBA 01/2022 - 01/2016
3	Selenious Acid (Selenite)IBA 10/2021 - 07/2018
3	methylselenic acidIBA 10/2021 - 01/2012
3	FumaratesIBA 01/2021 - 01/2019
3	GlutaminaseIBA 11/2019 - 01/2012
3	NucleotidesIBA 01/2019 - 06/2012
3	LipidsIBA 12/2018 - 06/2009
3	Citric Acid (Citrate)FDA LinkGeneric 01/2018 - 06/2009
2	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 12/2009
2	RNA (Ribonucleic Acid)IBA 01/2020 - 06/2012
2	Glycine (Aminoacetic Acid)FDA LinkGeneric 01/2019 - 04/2014
2	Proline (L-Proline)FDA Link 10/2018 - 06/2012
2	Reactive Oxygen Species (Oxygen Radicals)IBA 10/2018 - 06/2014
2	Amino Acids FDA Link 07/2017 - 01/2017
2	pyrimidineIBA 01/2017 - 10/2008
2	GlucansIBA 07/2016 - 11/2015
2	Pyruvate CarboxylaseIBA 02/2015 - 06/2009
2	NADP (NADPH)IBA 06/2014 - 01/2013
2	SeleniumIBA 06/2012 - 01/2006
1	DioxygenasesIBA 01/2022
1	NucleosidesIBA 01/2022
1	ChromatinIBA 01/2022
1	Tricarboxylic AcidsIBA 01/2022
1	Selenomethionine (Sethotope)FDA Link 10/2021
1	Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA 01/2021
1	Mitochondrial DNA (mtDNA)IBA 01/2021
1	beta-GlucansIBA 01/2021
1	pembrolizumabIBA 01/2021
1	alpha-hydroxyglutarateIBA 01/2021
1	HexosaminesIBA 01/2020
1	AsparagineIBA 01/2020
1	Ribose (D-Ribose)IBA 01/2020
1	Oxidoreductases (Dehydrogenase)IBA 01/2020
1	Inosine FDA Link 01/2020
1	Hepatocyte Nuclear FactorsIBA 01/2020
1	PolyaminesIBA 11/2019
1	Purine NucleotidesIBA 01/2019
1	Uncoupling Protein 2IBA 01/2019
1	purineIBA 01/2019
1	Serine (L-Serine)FDA Link 01/2019
1	Prolyl Hydroxylases (Prolyl Hydroxylase)IBA 10/2018
1	CollagenIBA 10/2018
1	Ketoglutaric Acids (Ketoglutaric Acid)IBA 10/2018
1	Sodium SeleniteIBA 07/2018
1	Fatty Acids (Saturated Fatty Acids)IBA 01/2018
1	ArsenicIBA 11/2017
1	Glutathione (Reduced Glutathione)IBA 11/2017
1	Cell ExtractsIBA 07/2017
1	Tissue ExtractsIBA 07/2017
1	ElementsIBA 07/2017
1	Protein Hydrolysates FDA Link 07/2017
1	Hydroxymethylglutaryl-CoA SynthaseIBA 01/2017
1	Alanine (L-Alanine)FDA Link 01/2017
1	AntioxidantsIBA 07/2016
1	itaconic acidIBA 07/2016
1	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 07/2016
1	HDL LipoproteinsIBA 01/2016
1	SulfurIBA 01/2016
1	CreatinineIBA 01/2016
1	Biomarkers (Surrogate Marker)IBA 01/2016

Therapy/Procedure

7	Therapeutics 01/2020 - 12/2004
2	Immunotherapy 01/2021 - 11/2015
2	Drug Therapy (Chemotherapy) 01/2017 - 11/2015